Mirela Viorica DĂNILĂ, MD, PhD


Work experience
  1. 2002 - present, Assistant Professor Department of Gastroenterology and Hepatology "Victor Babes" University of Medicine and Pharmacy Eftimie Murgu nr 2, Timişoara (Romania)
  2. 1997 - 2002, Fellow in Gastroenterology Clinic County Hospital Nr. 1 Timişoara, Bv. Liviu Rebreanu nr. 156, Timişoara (Romania)
  3. 1991 - 1997, Family Doctor 17 Medical Dispensary, Timişoara (Romania)
  4. 1987 – 1990, Intern Clinical County Hospital Brasov, Calea Bucureşti nr. 25-27, Brasov (Romania)

Education and training
  1. 2008 Senior Consultant Gastroenterology "Victor Babes" University of Medicine and Pharmacy Timişoara (Romania), ISCED 5
  2. 2000 PhD Medical Sciences - Gastroenterology "Victor Babes" University of Medicine and Pharmacy Timişoara (Romania), ISCED 6
  3. 2002 Specialist Gastroenterology "Victor Babes" University of Medicine and Pharmacy Timişoara (Romania), ISCED 5
  4. 1987 Medical Doctor Faculty of General Medicine University of Medicine and Pharmacy Timişoara (România), ISCED 5

Scientific activity

       Postgraduate courses
  1. 2000 – Course of General Ultrasound of the University of Medicine and Pharmacology Timisoara
  2. 2000 – Course of Endoscopy of the University of Medicine and Pharmacology Timisoara
  3. 2004 – The Postgraduated Course of Gastroentero-Hepatology (sponsored by The Holland Digestive Disease Week Fondation), Holland.
  4. 2006 – The Postgraduated Course of Endoscopy Ultrasound, University of Medicine and Pharmacy Craiova.
  5. 2009 – IBISCUS – Imaging School for Contrast-Enhanced Ultrasound, Bucuresti

       Abroad Scholarships
  1. nov. 2003 – one month scholarship at Liver Transplant Program Baylor University Medical Center, Dalas Texas, USA.

       Member of:
  1. Romanian Society of Gastroenterology and Hepatology
  2. Romanian Society of Endoscopy
  3. Romanian Society of Ultrasound in Medicine and Biology
  4. European Federation of Societies of Ultrasound in Medicine and Biology
  5. World Federation for Ultrasound in Medicine and Biology

       Publications:
  1. first author of over 30 scientific papers and co-author of over 190 scientific papers presented on national and international meetings.
  2. Author and co-author of 50 in extenso papers.
  3. Co-author of 2 medical books on abdominal ultrasound and gastroenterology.
  4. Co-author of 1 medical imaging DVD (ultrasound).

Main Scientific Publications
  1. Biopsia hepatică ecoghidată în diagnosticul hepatopatiilor cronice I. Sporea, Alina Popescu, Mirela Dănilă, Roxana Şirli, D. Săndesc; Revista Română de Ultrasonografie, 2001, vol.3, nr.1, p. 27-32
  2. Etiologia cirozelor hepatice în Banat Roxana Şirli, I. Sporea, E. Miuţescu, Alina Popescu, Mirela Dănilă, R. Străin; Revista pentru Educaţie Medicală Continuă, 4/2002, pag. 19-22
  3. The Prevalence of Helicobacter pylori Infection in Western Romania I. Sporea, Alina Popescu, Mark van Blankenstein, Roxana Sirli, M. Focsa, Mirela Danila; Romanian Journal of Gastroenterology, March 2003, vol.12 No.1, 15-18
  4. Frecvenţa şi severitatea infecţiei bivirusale HBV+HDV în Clinica de Gastroenterologie şi Hepatologie Timişoara Roxana Şirli, Mirela Dănilă, Alina Popescu, I. Sporea; Revista pentru Educaţie Medicală Continuă, 2004, vol. 3, nr.1, p. 11-14 (articol)
  5. Tratamentul actual al hepatitei cronice virusale HBV Ag Hbe pozitivă Mirela Dănilă, Roxana Şirli, Alina Popescu, I. Sporea; Revista pentru Educaţie Medicală Continuă, 2004, vol. 3, nr.1, p. 18-23 (articol)
  6. Peg Interferon Alpha 2a (40 kDa) in Patients on Chronic Haemodialysis with Chronic C Hepatitis. Preliminary Results I. Sporea, Roxana Sirli, O.Golea, Camelia Totolici, Mirela Danila, Alina Popescu; Roumanian Journal of Gastroenterology, 2004, 2, 99-102
  7. Ultrasound Assisted Liver Biopsy for the Staging of Diffuse Chronic Hepatopathies I. Sporea, Alina Popescu, Roxana Sirli, Mirela Danila, M. Străin; Roumanian Journal of Gastroenterology, 2004, 4, 287-290
  8. Colonoscopy in Romania I. Sporea, Alina Popescu, Mirela Danila, Roxana Sirli, Chadi Abou Salha; Roumanian Journal of Gastroenterology, 2005, 1, 15-18
  9. Assesment of the quality of colonoscopy in Romania I. Sporea, Alina Popescu, Roxana Sirli, Mirela Danila,; Roumanian Journal of Gastroenterology, 2005, 3, 303-308 (articol)
  10. Sedation during colonoscopy I. Sporea, Alina Popescu, D. Sandesc, C.A. Salha, Roxana Sirli, Mirela Danila; Roumanian Journal of Gastroenterology, 2005, 2, 195-198
  11. Comparative study concerning the efficacy of Peg-IFN alpha-2a versus Peg-IFN alpha-2b on the early virological response (EVR) in patients with chronic viral C hepatitis. Sporea I, Danila M, Sirli R et al.; J Gastrointestin Liver Dis 2006 Jun; 15(2):125-30
  12. Colonoscopia virtuală – viitorul screening-ului colo-rectal? Alina Popescu, I. Sporea, N. Bolog, C. Cernescu, Mirela Dănilă, Roxana Şirli; Revista pentru educaţie medicală continuă, 2006, vol.5, nr.3, p. 20-25
  13. Optimizarea tratamentului şi noi terapii în hepatita cronică virală C Roxana Şirli, I.Sporea, Mirela Danilă, Alina Popescu; Revista pentru educaţie medicală continuă, 2006, vol.5, nr.3, p. 26-31
  14. Rolul ecografiei cu substanţă de contrast (CEUS) în evaluarea tumorilor hepatice Mirela Dănilă, I.Sporea, Roxana Şirli, Alina Popescu; Revista pentru educaţie medicală continuă, 2006, vol.5, nr.3, p. 36-40
  15. Factors associated with failure of Liver Stiffness measurement using Transient Elastography R. Şirli, I. Sporea, A. Deleanu, A. Tudora, S. Bota, A. Popescu, M. Dănilă.; Timisoara Medical Journal 2009: 49 (1); 34-38.
  16. Liver stiffness assessment by means of trasnsient elastography (FibroScan®) in patients with liver cirrhosis – a predictor of portal hypertension? Şirli R, Raţiu I, Deleanu A, Sporea I, Bota S, Dănilă M, Popescu A. ; Medical Ultrasonography. 2009: 11 (1);5-10
  17. Contrast enhanced ultrasound in the assessment of focal liver lesions Popescu A, Sporea I, Şirli R, Dănilă M, Bota S, Guţă A.; Medical Ultrasonography. 2009: 11 (1);11-16
  18. Ecografia cu substanţă de contrast (CEUS) în patologia abdominală Sporea I, Dănilă M, Popescu A, Şirli R; Ed. Mirton Timişoara 2009. ISBN 978-973- 52-0612-3
  19. Current situation of colonoscopy in Romania - 3 years of colonoscopy performance I. Sporea, Alina Popescu, Roxana Sirli, Mirela Danila, Corina Vernic,; Rom. J. Intern Med. 2009 47 (1); 19-24
  20. Usefulness of contrast enhanced ultrasound for the evaluation of blunt abdominal trauma Sirli R., Sporea I, Popescu A, Danila M.; Medical Ultrasonography. 2009: 11 (2); 25-30
  21. The value of transabdominal ultrasound for assessment of the severity of liver steatosis as compared to liver biopsy Sporea I, Roxana Şirli, Elena Başa, Maria Cornianu, Alina Popescu, Mirela Dănilă and Mircea Focşa; Central European Journal of Medicine, Volume 4, Number 4 / December, 2009 pag 490-495
  22. Percutaneous Ethanol Injection Therapy in the Treatment of Hepatocarcinoma - Results Obtained from a Series of 88 Cases Mirela Dănilă, Ioan Sporea, Roxana Şirli, Alina Popescu; J Gastrointestin Liver Dis 2009; 18 3, 317-322
  23. The role of contrast-enhanced ultrasonography with second generation contrast agents in the evaluation of focal splenic lesions Alina Popescu, Ioan Sporea, Roxana Şirli, Mirela Dănilă, Diana Nicoliţă, Alina Martie; Medical Ultrasonography 2009, Vol. 11, no. 3, 61–65
  24. Contrast enhanced ultrasound evaluation of the kidney Roxana Şirli, Ioan Sporea, Alina Popescu, Mirela Danila; Medical Ultrasonography. 2009: 11 (4); 47-54.
  25. Acoustic Radiation Force Impulse (ARFI) – a new modality for the evaluation of liver fibrosis Ioan Sporea, Roxana Şirli, Alina Popescu, Mirela Danilă; Medical Ultrasonography 2010, Vol. 12, no. 1, 26-31
  26. The role of contrast enhanced ultrasound (ceus) in the assessment of liver nodules in patients with cirrhosis Mirela Danila, Ioan Sporea, Roxana Sirli, Alina Popescu, Madalina Sendroiu, Alina Martie; Medical Ultrasonography 2010, Vol. 12, no. 2, 145-149
  27. Spleen assessment by Acoustic radiation Force Impulse Elastography (ARFI) for prediction of liver cirrhosis and portal hypertension Bota S, Sporea I, Sirli R, Popescu A, Danila M, sendroiu M, Focsa M; Medical Ultrasonography 2010; 12 (3): 213-215
  28. Contrast enhanced ultrasound (CEUS) in the evaluation of liver metastases Danila M, Popescu A, Sirli R, Sporea I, Martie A, Sendroiu M; Medical Ultrasonography 2010; 12 (3): 233-237
  29. Acoustic Radiation Force Impulse Elastography as Compared to Transient Elastography and Liver Biopsy in Patients with Chronic Hepatopathies. Sporea I, Sirli RL, Deleanu A, Popescu A, Focsa M, Danila M, Tudora A.; Ultraschall Med. 2011 Jan;32 Suppl 1:S46-52. [Epub ahead of print 2010 Jul 5]
  30. Can Acoustic Radiation Force Impulse Elastography (ARFI) predict the complications of liver cirrhosis? Şirli R, Sporea I, Bota S, Ciof O, Popescu A, Danilă M; Rom J Intern Med, 2010, 7(5), 15-20
  31. Contrast Enhanced Ultrasound in focal liver lesions – a cost efficiency study Roxana Şirli, Ioan Sporea, Alina Martie, Alina Popescu, Mirela Dănilă; Medical Ultrasonography 2010, 12 (4), 280-285
  32. How useful is contrast enhanced ultrasonography for the characterization of focal liver lesions? Sporea I, Sirli R, Martie A, Popescu A, Danila M.; J Gastrointestin Liver Dis. 2010 Dec;19(4):393-8
  33. Thyroid Stiffness Assessment by Acoustic Radiation Force Impulse Elastography (ARFI). Sporea I, Vlad M, Bota S, Sirli RL, Popescu A, Danila M, Sendroiu M, Zosin I.; Ultraschall Med. 2011 Feb 14. [Epub ahead of print]
  34. The mean values of liver stiffness assessed by Acoustic Radiation Force Impulse elastography in normal subjects. Popescu A, Sporea I, Sirli R, Bota S, Focsa M, Danila M, Nicolita D, Martie A, Sendroiu M, Juchis A.; Med Ultrason. 2011 Mar;13(1):33-7.
  35. Contrast Enhanced Ultrasound for the Characterization of Focal Liver Lesions. Sporea I, Badea R, Martie A, Sirli R, Socaciu M, Popescu A, Danila M.; Med Ultrason. 2011 Mar;13(1):38-44.
  36. Contrast Enhanced Ultrasound for the Diagnosis of Liver Hemangiomas in Clinical Practice. Sirli R, Sporea I, Popescu A, Dănilă M, Martie A, Bota S, Jurchis A, Sendroiu M.; Med Ultrason. 2011 Jun;13(2):95-101.
  37. The Value of Contrast Enhanced Ultrasound in the Evaluation of the Nature of Portal Vein thrombosis. Dănilă M, Sporea I, Popescu A, Sirli R, Sendroiu M.; Med Ultrason. 2011 Jun;13(2):102-7.
  38. Contrast Enhanced Ultrasound for the Characterization of Hepatocellular Carcinoma. Martie A, Sporea I, Popescu A, Sirli R, Dănilă M, Serban C, Ardelean M, Bota S, Sendroiu M, Chisevescu D.; Med Ultrason. 2011 Jun;13(2):108-13.
  39. Factors that Influence the Correlation of Acoustic Radiation Force Impulse (ARFI), Elastography with Liver Fibrosis. Bota S, Sporea I, Sirli R, Popescu A, Danila M, Sendroiu M.; Med Ultrason. 2011 Jun;13(2):135-40.
  40. Is ARFI Elastography Reliable for Predicting Fibrosis Severity in Chronic HCV Hepatitis? Sporea I, Sirli R, Bota S, Fierbinteanu-Braticevici C, Petrisor A, Badea R, Lupsor M, Popescu A, Danila M.; World J Radiol. 2011 Jul 28;3(7):188-93.
  41. How efficient is acoustic radiation force impulse elastography for the evaluation of liver stiffness? Sporea I, Badea R, Sirli R, Lupsor M, Popescu A, Danila M, et al.; Hepat Mon. 2011;11(7):532-8.
  42. A new scoring system for prediction of fibrosis in chronic hepatitis C. Bota S, Sirli R, Sporea I, Focsa M, Popescu A, Danila M, et al.; Hepat Mon. 2011;11(7):548-5.
  43. The Influence of Liver Residual Mass on the Values of Acoustic Radiation Force Impulse Elastography (ARFI) in Cirrhotic Patients. Bota S, Sporea I, Sirli R, Popescu A, Dănilă M, Sendroiu M.; Med Ultrason. 2011 Sep;13(3):195-9.
  44. Is it better to use two elastographic methods for liver fibrosis assessment? Sporea I, Şirli R, Popescu A, Bota S, Badea R, Lupşor M, Focşa M, Dănilă M; World J Gastroenterol 2011; 17(33): 3824-3829
  45. Response to Standard of Care Antiviral Treatment in Patients with HCV Liver Cirrhosis - A Systematic Review. Bota S, Sporea I, Popescu A, Sirli R, Neghina AM, Danila M, Strain M.; J Gastrointestin Liver Dis. 2011 Sep;20(3):293-8
  46. Value of Acoustic Radiation Force Impulse Elastography for the Assessment of Ascites Syndrome Bota S, Sporea I, Sirli R, Popescu A, Danila M, Sendroiu M.; World J Radiol 3(8):205 -209.
  47. The Correlation of Il28B Genotype With Sustained Virologic Response In Romanian patients With Chronic Hepatitis C. Sporea I, Popescu A, Curescu M, Sirli R, Dan I, Goldis A, Gradinaru O, Ardelean M, Danila M, Bota S, Deleanu A.; Hepat Mon. 2011 Dec;11(12):975-9.
  48. Intra- and Interoperator Reproducibility of Acoustic Radiation Force Impulse (ARFI) Elastography-Preliminary Results. Bota S, Sporea I, Sirli R, Popescu A, Danila M, Costachescu D.; Ultrasound Med Biol. 2012 Jul;38(7):1103-8
  49. Contrast Enhanced Ultrasound for the evaluation of focal liver lesions in daily practice. A multicentre study. Sporea I, Badea R, Martie A, Dumitru E, Ioanitescu S, Sirli R, Socaciu M, Popescu A, Dănilă M, Voiculescu M.; Med Ultrason. 2012 Jun;14(2):95-100
  50. Can ARFI elastography predict the presence of significant esophageal varices in newly diagnosed cirrhotic patients? Bota S, Sporea I, Sirli R, Focsa M, Popescu A, Danila M, Strain M.; Ann Hepatol. 2012 Jul;11(4):519-25.
  51. Acoustic Radiation Force Impulse Elastography for fibrosis evaluation in patients with chronic hepatitis C: An international multicenter study. Sporea I, Bota S, Peck-Radosavljevic M, Sirli R, Tanaka H, Iijima H, Badea R, Lupsor M, Fierbinteanu-Braticevici C, Petrisor A, Saito H, Ebinuma H, Friedrich-Rust M, Sarrazin C, Takahashi H, Ono N, Piscaglia F, Borghi A, D'Onofrio M, Gallotti A, Ferlitsch A, Popescu A, Danila M.; Eur J Radiol. 2012 Dec;81(12):4112-8 Sep 20. pii: S0720-048X(12)00405-6. doi: 10.1016/j.ejrad.2012.08.018.
  52. The Contribution of Contrast Enhanced Ultrasound for the characterization of benign liver lesions in clinical practice - a monocentric experience. Martie A, Bota S, Sporea I, Șirli R, Popescu A, Danila M.; Med Ultrason. 2012 Dec;14(4):283-7
  53. How often hepatocellular carcinoma has a typical pattern in contrast enhanced ultrasound Martie A, Sporea I, Șirli R, Popescu A, Dănilă M; Maedica, A Journal of Clinical Medicine 2012; 7(3): 236-240
  54. Predictive factors for severe evolution in acute pancreatitis and a new score for predicting a severe outcome Bota S, Sporea I, Sirli R, Popescu A, Strain M, Focsa M, Danila M, Chisevescu D; Ann Gastroenterol 2013; 26 (2): 1-7
  55. The Influence of Food Intake on Liver Stiffness Values Assessed by Acoustic Radiation Force Impulse Elastography-Preliminary Results. Popescu A, Bota S, Sporea I, Sirli R, Danila M, Racean S, Suseanu D, Gradinaru O, Ivascu Siegfried C.; Ultrasound Med Biol. 2013 Apr;39(4):579-84
  56. Predictive factors for severe evolution in acute pancreatitis and a new score for predicting a severe outcome Bota S, Sporea I, Sirli R, Popescu A, Strain M, Focsa M, Danila M, Chisevescu D; Ann Gastroenterol 2013; 26 (2): 1-7
  57. The influence of aminotransferase levels on liver stiffness assessed by Acoustic Radiation Force Impulse Elastography: A retrospective multicentre study. Bota S, Sporea I, Peck-Radosavljevic M, Sirli R, Tanaka H, Iijima H, Saito H, Ebinuma H, Lupsor M, Badea R, Fierbinteanu-Braticevici C, Petrisor A, Friedrich-Rust M, Sarrazin C, Takahashi H, Ono N, Piscaglia F, Marinelli S, D'Onofrio M, Gallotti A, Salzl P, Popescu A, Danila M.; Dig Liver Dis. 2013 Mar 16. doi:pii: S1590-8658(13)00061-3. 10.1016/j.dld.2013.02.008.
  58. Severe adverse events during antiviral therapy in hepatitis C virus cirrhotic patients: A systematic review. Bota S, Sporea I, Sirli R, Popescu A, Neghină AM, Dănilă M, Străin M.; World J Hepatol. 2013 Mar 27;5(3):120-6